Response from Dr. Helz (Hetz Lab) to questions of a international science blog

Laboratory statement

Recently, an anonymous blogger questioned some of our previous publications because of splicing of Western blot-gel images. We would like to state that this is a normal practice and never represented an issue for our group. This has been done in many of our studies based on the fact that the rearrangement of the images is done properly. However, because of changes in editorial policies in the last years in many Journals, in all our recent publications we now indicate in the legend the gels that were spliced and also provide full scan of gels (see examples in Castillo et al 2011 EMBO J and Rodriguez et al., 2012 EMBO J). We have also generated a data repository in our website to give open access to full scans of all our publications.

We identified through this blog two unintentional errors in two publications (Hum. Mol. Gen. 2012; 21(10):2245-62 and J. Biol. Chem. 2005; 280: 42960-42970) that have been corrected through the submission of an errata to the corresponding Journals. We regret the language used in this anonymous blog because it has a clear intention of generating damage to our group.




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